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Journal of the american society of nephrology skip to main page content home author info reprints/permissions editorial board subscribe feedback alerts help current issue archives jasn express online submission 2011 jasn impact factor 9. 663 search go advanced user name password sign in randomized, controlled trial of prednisone, cyclophosphamide, and cyclosporine in lupus membranous nephropathy howard a. Austin iii *, gabor g. order diflucan online Illei † ‡ , michelle j. Braun * and james e. diflucan for sale Balow * *national institute of diabetes and digestive and kidney diseases, †national institute of arthritis and musculoskeletal and skin diseases, and ‡national institute of dental and craniofacial disorders, national institutes of health, bethesda, maryland correspondence: dr. Howard a. Austin, iii, national institutes of health, kidney disease section, niddk, building 10, crc 5-2551, bethesda, md 20892-1455. Generic synthroid online Phone: 301-435-5055; fax: 301-480-1640; e-mail: howarda{at}bdg10. buy diflucan Niddk. Nih. Gov received for publication june 30, 2008. Accepted for publication november 16, 2008. Abstract patients with lupus membranous nephropathy (lmn) are at substantial long-term risk for morbidity and mortality associated with protracted nephrotic syndrome, including esrd. generic diflucan online The optimal treatment for this condition is controversial. Forty-two patients with lmn participated in a randomized, controlled trial to compare adjunctive immunosuppressive drugs with prednisone alone. buy diflucan online Adjunctive regimens included either cyclosporine (csa) for 11 mo or alternate-month intravenous pulse cyclophosphamide (ivcy) for six doses; the control group received alternate-day prednisone alone. Median proteinuria was 5. 4 g/d (range 2. Order diflucan online 7 to 15. 4 g/d). We assessed the primary outcome, time to remission of proteinuria during the 12-mo protocol, by univariate survival analysis. At 1 yr, the cumulative probability of remission was 27% with prednisone, 60% with ivcy, and 83% with csa. Although both ivcy and csa were more effective than prednisone in inducing remissions of proteinuria, relapse of nephrotic syndrome occurred significantly more often after completion of csa than after ivcy. generic diflucan By multivariate survival analysis, treatment with prednisone and high-grade proteinuria (>5 g/d) but not race or ethnicity were independently associated with a decreased probability of remission. Adverse effects during the 12-mo protocol included insulin-requiring diabetes (one with prednisone and two with csa), pneumonia (one with prednisone and two with csa), and localized herpes zoster (two with ivcy). diflucan online In conclusion, regimens containing csa or ivcy are each more effective than prednisone alone in inducing remission of proteinuria among patients with lmn. Copyright ⩠2009 by the american society of nephrology related articles up front matters - editorials: treatment of membranous lupus nephritis: where are we now? Laurence h. Beck, jr. And david j. Salant jasn april 2009 20: 690 - 691 ; published ahead of print march 11, 2009, doi:10. 1681/asn. 2009020216 [ full text ] ⫠previous | next article ⻠table of contents this article published online before print march 18, 2009, doi: 10. 1681/asn. 2008060665 jasn april 2009 vol. diflucan for sale 20 no. 4 901-911 ⻠abstract full text classifications clinical research services email this article to a colleague alert me when this article is cited alert me if a correction is posted similar articles in this journal similar articles in web of science similar articles in pubmed download to citation manager citing articles load citing article information citing articles via web of science citing articles via google scholar google scholar articles by austin, h. diflucan no prescription A. Articles by balow, j. E. Search for related content pubmed pubmed citation articles by austin, h. A. Articles by balow, j. E. diflucan for sale Related content related articles in this journal load related web page information current issue september 28, 2012, 23 (10) alert me to new issues of jasn home current issue archives jasn express online submission author info advertising editorial board subscribe feedback alerts help copyright ⩠2012 by the american society of nephrology. diflucan for sale Print issn: 1046-6673 online issn: 1533-3450. 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